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Side Effects of This Medicine
Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Zyban.
< br> The most common side effects are:
Dry mouth and sleeplessness
These are generally mild and usually disappear after a few weeks. If you have difficulty sleeping, avoid taking Zyban close t o bedtime and ask your doctor about reducing your dosage.

More common side effects may include:
Abdominal pain, abnormal dreams, anxiety, constipation, diarrhea, disturbed concentration , dizziness, joint pain, increased cough, itching, nasal inflammation, nausea, nervousness, rash, sore throat

Cautions
Your doctor should check your progress at regular visits, especially during the first few months of treatment with this medicine. The amount of Zyban you take may have to be changed often to meet the needs of your condition and to help avoid unwanted effects.

Do not take Zyban within 14 days of taking an MAO inhibitor.

Zyban is sold under different brand names for different uses. If you are already taking medicine for mental depression or to help you stop smoking, discuss this with your health care professional before taking Zyban. It is very important that you receive only o ne prescription for Zyban at a time.

Possible food and drug interactions
When you are taking Zyban, it is especially important that your health care professional know if you are taking any of the following:

- Alcohol or
- Antipsychotics (medicine for mental illness) or
- Corticosteriods(cortisone-like medicine) or
- Fluoxetine (e.g., Prozac) or
- Lithium (e.g., Lithane) or
- Maprotiline (e.g., Ludiomil) or
- Theophylline (e.g., S omophyllin-T) or
- Trazodone (e.g., Desyrel) or
- Ritonavir (e.g., Norvir)¡XUsing these medicines with Zyban may increase the risk of seizures

Before Using This Medicine
Allergies¡XTell your doctor if you have ever had any unusual or allergic reaction to Zyban. Also tell your health care professional if you are allergic to any other substances, such as foods, preserva ives, or dyes.

Overdose
It is especially important to check with your doctor before combining Zyban with the following:

- Alcohol
- Amantadine (Symmetrel)
- Antidepressants such as Norpramin, Pamelor, Pa xil, Prozac, Tofranil, and Zoloft
- Beta blockers (heart and blood pressure medications) such as Inderal, Lopressor, and Tenormin
- Carbamazepine (Tegretol)
- Cimetidine (Tagamet)
- Cyclophosphamide (Cytoxan)
- Heart-stabilizing drugs such as Rythmol and Tambocor
- Levodopa (Dopar, Larodopa, Sinemet)
- Major tranquilizers such as Haldol, Risperdal and Thorazine < br> - MAO inhibitors such as the antidepressants Nardil and Parnate
- Orphenadrine (Norflex)
- Phenobarbital
- Phenytoin (Dilantin)

How should this medicine be used?
Zyban comes as a tablet to take by mouth. It is usually taken one to three times a day and may be taken with or without food. Do not crush, chew, or divide Wellbutrin SR or Zyban tablets. Follow the d irections on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take Zyban exactly as directed.

Continue to take Zyban even if you feel well. Do not stop taking Zyban without talking to your doctor, especially if you have taken large doses for a long time. Your doctor probably will want to decrease your dose gradually. This drug must be taken regularly for a few weeks before its full effect is felt.




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