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Significant Interactions:
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to c hange the dose, or other precautions may be necessary. When you are taking orlistat, it is especially important that your health care professional know if you are taking the following:

- Warf arin¡XOrlistat may decrease the absorption of vitamin K and may change your bleeding time

Precautions while Using this Medicine
It is very important that your doctor check your progress at regular visits to make sure that this medicine is working properly and to check for unwanted effects.

For patients with diabetes: Weight loss may result in an improvement in your condition, and your doctor may need to change your dose of oral diabetes medicine or insulin.

What special precautions should I follow?
Pregnancy¡XOrlistat has not been studied in pregnant women. However, orlistat may decrease the amount of certain vitamins that your body can absorb from the food you eat. Make sure you have discussed ith your doctor the use of this medication during pregnancy.

How should this medicine be used?
Orlistat prevents the absorption of some of the fat you eat. Therefore, you should take it during the meal or within 1 hour of eating. If you occasionally miss a meal or eat a meal that contains no fa t, you should skip the dose of orlistat.

Because orlistat may decrease the amount of some vitamins that your body can absorb from food, you will need to take a multivitamin supplement once a day. Take the vitamin supplement at least 2 hours before or after taking orlistat

Why is this drug prescribed?
Orlistat is used with a low-calorie diet to help you lose weight and to maintain your weight after weight loss. Orlistat is used in patients with a certain weight who may also have high blood pressure , diabetes, high cholesterol, or heart disease.

- Orlistat is in a class of drugs called lipase inhibitors. It works in your intestines, where it blocks some of the fat you eat from being abs orbed and disgested. This undigested fat is then removed in your bowel movements (BM).

What side effects can this medication cause?
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor as soon as possible if any of the following side effects occur:

- Bodyache; chills; cough; fever; headache; nasal congestion; runny nose; sneezing; sore throat

- Tightness in chest; tooth or gum problems ; troubled breathing; wheezing

- Bloody or cloudy urine; change in hearing ; contagious diarrhea; difficult or painful urination; earache; frequent ur ge to urinate; pain in ear




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