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Precautions Before Using This Medicine
Before taking cyclobenzaprine,

- tell your doctor and pharmacist if you are allergic to cyclobenzaprine or any other drugs.
- tell your doctor and pharmacist what prescription and nonpre scription drugs you are taking or have taken within the last 2 weeks, especially medications for depression, seizures, allergies, coughs, or colds; MAO inhibitors [phenelzine (Nardil), tranylcypromine (Parnate)]; sedatives; sleeping pills; tranquilizers; and vitamins.
- tell your doctor if you have an overactive thyroid gland, heart disease, glaucoma, or difficulty urinating.

Overdosage
Symptoms of Flexeril overdose may include:
- Agitation, coma, confusion, congestive heart failure, convulsions, dilated pupils, disturbed concentration, drowsiness, hallucinations, high or low te mperature, increased heartbeats, irregular heart rhythms, muscle stiffness, overactive reflexes, severe low blood pressure, stupor, vomiting

High doses also may cause any of the conditions li sted in "What Side Effects May Occur?"

Cautions
Cyclobenzaprine may cause dryness of the mouth. For temporary relief, use sugarless candy or gum, melt bits of ice in your mouth, or use a saliva substitute. However, if your mouth continues to feel d ry for more than 2 weeks, check with your medical doctor or dentist. Continuing dryness of the mouth may increase the chance of dental disease, including tooth decay, gum disease, and fungus infection s

Drug Interactions
Serious, potentially fatal reactions may occur if you take Flexeril with an antidepressant drug known as an MAO inhibitor (such as Nardil, Parnate) or if it has been less than 2 weeks since you last t ook an MAO inhibitor. You should closely follow your doctor's advice regarding discontinuation of MAO inhibitors before taking Flexeril. Avoid alcoholic beverages while taking Flexeril. If Flexeril is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Flexeril with the following: Bar biturates such as phenobarbital Guanethidine and other high blood pressure drugs Other drugs that slow the central nervous system, such as Halcion and Xanax Tramadol (Ultram)

What is this medicine
Flexeril - Cyclobenzaprine (sye-kloe-BEN-za-preen) is used to help relax certain muscles in your body. It helps relieve the pain, stiffness, and discomfort caused by strains, sprains, or injuries to y our muscles. However, this medicine does not take the place of rest, exercise or physical therapy, or other treatment that your doctor may recommend for your medical problem. Cyclobenzaprine acts on t he central nervous system (CNS) to produce its muscle relaxant effects. Its actions on the CNS may also cause some of this medicine's side effects.

Side Effects
The following side effects may mean that you are having a serious allergic reaction to the medicine. Get emergency help right away if any of them occur:
- Changes in the skin color of the face; f ast or irregular breathing; large swellings that look like hives on the face, eyelids, mouth, lips, and/or tongue; puffiness or swelling of the eyelids or the area around the eyes ; shortness of br eath, troubled breathing, tightness in chest, and/or wheezing; skin rash, hives, or itching




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